Micro Technologies in Medical applications
Microfluidic solutions for LoC / OoC systems
Microfluidics is the precise handling and control of small liquid volumes—typically in the microliter to nanoliter range—within microscopic channels and chambers. In Lab-on-a-Chip (LoC) systems, this enables faster diagnostics with less sample and lower cost. In Organ-on-a-Chip (OoC) platforms, it sustains living cell cultures with nutrient flow and mimics natural body movements like breathing or heartbeat—creating realistic tissue environments for drug testing and disease research.
Our microfluidic solutions are tailored to meet the specific demands of both LoC and OoC applications. We design and fabricate custom channel geometries, integrate membranes and sensors, and ensure reliable fluidic connections for seamless system operation.
Filter/membrane integration
Filter/membrane integration is essential in LoC and OoC systems because it adds control over what moves in and out of the fluid channels. In diagnostic applications, membranes act as physical barriers that separate blood cells from plasma, trap target biomarkers, or remove unwanted particles, ensuring cleaner and more accurate test results. In Organ-on-a-Chip platforms, porous membranes serve as a growth surface for cells while allowing nutrients, drugs, and waste products to pass between different tissue layers—just like in the human body.
We integrate custom membranes and micro-sieve structures into polymer chips. Our expertise ensures leak-proof sealing, precise pore sizing, and optimal surface properties—whether filtration, cell retention, or a functional growth interface is needed.
Sensor/ electrode integration
Sensors and electrodes transform passive microfluidic chips into active, intelligent devices. In LoC systems, embedded electrodes enable real-time detection of chemical changes, pH levels, or specific biomarkers—turning a simple fluid channel into a diagnostic tool. In OoC platforms, sensors monitor critical parameters like oxygen levels, cell metabolism, or electrical activity across tissue layers, providing continuous, non-invasive readouts of organ function.
Integrating custom metallic and conductive polymer microelectrodes directly into the chip architecture enables the chips to support electrochemical sensing, impedance measurements, and bio-signal monitoring with high sensitivity and repeatability.
Others
Beyond our core LoC and OoC developments, we actively pursue research and development in complementary medical device fields. We develop custom screen-printed electrodes (SPE) for low-cost, disposable biosensors used in point-of-care testing. We also have experience in manufacturing of miniaturized implantable neuro-stimulation electrodes designed for deep brain stimulation and peripheral nerve modulation, with a focus on long-term biocompatibility and high charge delivery.
Our expertise include fabrication of precision microtube and microwire-based metal stents for vascular and non-vascular interventions, combining high radial strength with exceptional flexibility. These initiatives reflect our broader commitment to advancing microengineering solutions across diagnostics, neuromodulation, and interventional medicine.
